Dominant mutations in COL4A1 lead to change of the basal membrane of capillaries resulting in microangiopathy. However, a genetic predisposition to disruptive lesions may be present. Disruptions are acquired lesions with very low recurrence risk. prenatal infection, hemorrhage, or ischemia and commonly involve the cerebellum. A disruption is defined as a congenital morphologic anomaly due to the breakdown of a body structure that had a normal developmental potential. A malformation is defined as a congenital morphologic anomaly of a single organ or body part due to cellular and molecular pathways involved in organogenesis the molecules in these pathways can be altered by gene mutations, teratogens, or combined effects. The diagnosis of congenital cerebellar anomalies should include the differentiation between inherited (developmental) and acquired (disruptive) abnormalities. Cerebellar malformations versus cerebellar disruptions Here, we will 1) differentiate between cerebellar malformations and cerebellar disruptions and 2) define and discuss various morphological cerebellar patterns including cerebellar agenesis, cerebellar hypoplasia, pontocerebellar hypoplasia, cerebellar dysplasia, cerebellar dysmorphia, and cerebellar atrophy. Precision in the use of language, whether verbal or written, is a reflection of precision in scientific thought and patient care. Semantics does matter in medical and scientific communications. ![]() This leads to confusion and may result in misdiagnosis. Sometimes in the daily clinical work as well as in the scientific literature, the terms mentioned above are used interchangeably. An accurate diagnosis of these complex abnormalities is important for: 1) early institution of the correct therapy, 2) prediction of the prognosis, and 3) counseling of the family including inheritance pattern and risk of recurrence. The familiarity with the diagnostic criteria is mandatory for a correct diagnosis and a targeted work-up to avoid unnecessary investigations. These patterns have specific differential diagnoses. Various morphological patterns have been described on neuroimaging including cerebellar hypoplasia, cerebellar agenesis, pontocerebellar hypoplasia, cerebellar dysplasia, cerebellar dysmorphia, and cerebellar atrophy. Diagnostic criteria for numerous morphological anomalies of the cerebellum are based on neuroimaging findings. Neuroimaging plays a key role in the diagnostic work-up of morphological abnormalities of the cerebellum. New classifications and checklists of morphological abnormalities of the cerebellum have been proposed. ![]() Progress in neuroimaging techniques and genetic analysis has led to a significant improvement in definition of morphological abnormalities of the cerebellum.
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![]() The Girsan MC28 is a polymer framed striker fired 9mm pistol. GIRSAN MC 28 V2 OPTIC READY Black 9mm Pistol 4.25″. EAA GIRSAN MC28 SA-T 9mm Luger Semi Auto Pistol, 4.25" Barrel, 15+1 Rounds, Red Dot Optic Polymer Frame, Two Tone Finish. Caliber – 9MM Luger (9×19 mm) OA Length – 7.6 inches. The MC28 incorporates design elements from some of the best-selling handguns on the market today. 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Glory to ccp in chinese 5 minutes ago 12 dpo bfn success storiesEAA GiRSAN MC28SA-TV BX by Graham Baates USA – -()- The GiRSAN MC28 was an affordable and popular pistol to those who knew it. Whether for engineering, architectural, construction, manufacturing or other types, layers were used to show different aspects on the drawing. These sheets were then overlaid one on top of another to produce final drawings. The layers were often drawn on separate transparent sheets of paper. Traditional manual drafting used a similar approach. Layers help organize drawings by allowing users to place and manage related entities. One of LibreCAD’s key features is the ability to use layers. A maximum of eight user defined colors can be added. User defined colors can be modified by right-clicking on a user defined color and selecting a new hue and value. User defined colors are created by clicking the Add button and then selecting the hue and value from the color selection tool. Selecting ”Custom” will allow a selection from a palette of 36 colors and shades of grey or from a user defined colors. If the block’s color is subsequently changed all entities in the block will be assigned the block’s color. When editing a block, selecting ”By Block” will assign the color that was defined for the block to the added entity. If the layer’s selected color is subsequently changed all entities on the layer will be assigned the layer’s color. Selecting ”By Layer” will assign the color that was defined for the layer (see above) to the entity. ![]() The drop-down menu allows the color to be selected ”By Layer”, ”By Block”, from the ”Custom” color selector, or chosen quickly from one of the 16 pre-defined colors: The color for an entity can be selected from the ”Color” selection drop-down menu. ![]() Review Blackmagic Disk Speed Test files or folders, click Complete Uninstall button and then click Yes in the pup-up dialog box to confirm Blackmagic Disk Speed Test removal. The program lies within System Tools, more precisely Benchmark. ![]() The most popular versions among Blackmagic Disk Speed Test for Mac users are 2.2 and 2.1. We cannot confirm if there is a free download of this app available. As were in the Mac Pro forum I thought it was clear but re-reading my post, I can see that it might be a bit ambiguous. The only limitation of this tool is that it’s designed for people. Blackmagic Disk Speed Test 3.4 for Mac could be downloaded from the developer's website when we last checked. In the BlackMagic disk speed test Im only getting around 100MB/sec read/write speeds. It’s a useful free utility is designed to test the speed of SD and microSD cards. Blackmagic Disk Speed Test is one of the best tools if you own a Mac. Launch MacRemover in the dock or Launchpad, select Blackmagic Disk Speed Test appearing on the interface, and click Run Analysis button to proceed. Here are the 5 best free SD Card speed testing tools: 1. Download MacRemover and install it by dragging its icon to the application folder. Blackmagic Disk Speed Test Mac Direct Download 1. Resolve Studio 18.0b4 Build 23 Dell XPS 8700 i7-4790 4 core, 24GB RAM, 2 x internal Samsung Evo SSDs, GTX1060/6GB (512. Now let’s see how it works to complete Blackmagic Disk Speed Test removal task. MacRemover is a lite but powerful uninstaller utility that helps you thoroughly remove unwanted, corrupted or incompatible apps from your Mac. Here MacRemover is recommended for you to accomplish Blackmagic Disk Speed Test uninstall within three simple steps. If you intend to save your time and energy in uninstalling Blackmagic Disk Speed Test, or you encounter some specific problems in deleting it to the Trash, or even you are not sure which files or folders belong to Blackmagic Disk Speed Test, you can turn to a professional third-party uninstaller to resolve troubles. ![]() This gives the figures some color, and is not 100% black and white. The figures are usually moved behind a thin screen and is not entirely a show of shadows as it is more of a silhouette shadow. (皮影戏, pí yĭng xì) is a shadow theatre using leather puppets.TerminologyĪ number of terms are used to describe the different forms. A large repertoire of some 300 scripts of the southern school of drama used in shadow puppetry and dating back to the fourteenth and fifteenth centuries has been preserved in Taiwan and is considered to be a priceless cultural asset. Taiwan's shadow plays are accompanied by Chaochow melodies which are often called "priest's melodies" owing to their similarity with the music used by Taoist priests at funerals. As shadow puppetry is based on light penetrating through a translucent sheet of cloth, the "shadows" are actually silhouettes seen by the audience in profile or face on. Traditionally, the eight to 12-inch puppet figures, and the stage scenery and props such as furniture, natural scenery, pagodas, halls, and plants are all cut from leather. Older puppeteers estimate that there were at least a hundred shadow puppet troupes in southern Taiwan in the closing years of the Qing. Commonly known as leather monkey shows or leather shows, the shadow plays were popular in Tainan, Kaohsiung, and Pingtung as early as the Qing dynasty (1644-1911 A.D.). The origins of Taiwan's shadow puppetry can be traced to the Chaochow school of shadow puppet theatre. Ĭhinese shadow puppetry is shown in the 1994 Zhang Yimou film To Live. In Gansu province, it is accompanied by Daoqing music, while in Jilin, accompanying Huanglong music forms some of the basis of modern opera. Today, puppets made of leather and moved on sticks are used to tell dramatic versions of traditional fairy tales and myths. The storytellers generally used the art to tell events between various war kingdoms or stories of Buddhist sources. The earliest shadow theatre screens were made of mulberry paper. Later, it was introduced to other Southeastern Asian countries. It was spread by the conquering Mongols to distant countries like Persia, Arabia, and Turkey. In the 13th century, the shadow show became a regular recreation in the barracks of the Mongolian troops. During the Ming Dynasty there were 40 to 50 shadow show troupes in the city of Beijing alone. Shadow theatre became quite popular as early as the Song Dynasty when holidays were marked by the presentation of many shadow plays. ![]() ![]() Using an oil lamp they made her shadow move, bringing her back to life. Her joints were animated using 11 separate pieces of the leather, and adorned with painted clothes. The officers made a shape of the concubine using donkey leather. The emperor was devastated, and he summoned his court officers to bring his beloved back to life. Shadow puppetry originated during the Han Dynasty when one of the concubines of Emperor Wu of Han died from an illness. 8 The Ottoman Shadow Play and its Turkish descendants.The principal differences between nang talung and wayang kulit gedek lie in the language used and in the repertoire of stories, which once again, has the Ramayana as its basic literary source. NangTailing and Wayang Kulit Gedek The figures used are smaller and flimsier and some puppets are carved en face. What is the difference between wayang kulit and Nang shadow? They offer obscene humour, often characteristic of nang talung and always loved by the audience. The popular characters are the stock clowns, such as Ai Nol, Ai Tong, Al Muang, and Ai Klang. They usually possess a movable, jointed arm controlled by a string.īeside this, what are the characters in Nang? Nang Talung is played with leather puppets, each representing a separate character, about 50 centimeters high.Nang means "leather" ("leather puppet" in this case), and in common usage refers to a dance-drama shadow puppet show.Īlso, what are the two types of Nang? Two Types of the Nang: Puppets are made of painted buffalo hide, while the story is narrated by songs, chants and music. ?, pronounced ) is a form of shadow play found in Thailand. Correspondingly, what is nang shadow puppet? ![]() Hurry, deals going fast! Visit AliExpress right now, your NO.1 helper for shopping in and. To get more inspirational shopping ideas, watch live stream and browse Feed chanel in order to pick most-loved items in. ![]() Feeling hard to judge the quality of an item? Browse customer reviews before a purchase! 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Uyesee accumulated wealthy experience on Linux and Android system development. Our main focus is on android based smart devices, including hardware and software which allows us to adapt swiftly to make changes in the OTT and Hybrid Android boxes to match the specified needs for our customers. We also have a wide range of product lines for your potential customers, such as content providers, service providers and telco operators. SHENZHEN Uyesee Co., Ltd is one of the leading OEM/ODM manufacturer specialized in providing an open android based hardware and software platform for OTT Android boxes with embedded digital TV tuner in it. ![]() Some users might have to pay charges depending on what charges their particular carrier adds on.It's not possible to use this app to make any emergency calls to 911 unfortunately.Along with calls, the app can also sends text messages.The app will give users a free United States phone number.They can call back home when they're traveling abroad for free. Users can receive calls from other countries for free. Communicating internationally is easy here.There is a system set up with this app whereby users can accumulate calling credits so that they can then use those credit to make international calls themselves for free. Callers can call you from international locations for free. ![]() You can also send messages that include pictures or videos. You get a free phone number, and you can send texts and make calls to United States and Canadian recipients. There are numerous features offered here. If you have a microphone built into a device like a tablet, you can use your tablet to make calls and send texts on your Talkatone phone number. It can turn other devices into phones as well. The Talkatone Free Calls and Texting app is more than just a phone. The number should be a United States phone number. It's great to know that you're going to get a free phone number along with using this app. Those who want to use the service will first need to set up an account. It's a way that smartphone users can communicate with those in other countries or communicate while they're traveling without having to worry about the roaming charges or other international charges they might have to pay for if they made calls using regular cell service. This is convenient because it will work anywhere in the world. And when they don’t quite fit your needs, cheap providers like Rebtel bridge the gap to make sure you are kept fully in the loop with your friends and family abroad.Talkatone Free Calls and Texting is an app that allows users to make phone calls and send text messages over a WiFi connection. So whilst totally free Wi-Fi services do have their limitations. It’s easy to set up you can try the service free of charge and use Wi-Fi networks to avoid expensive roaming charges. Phone calls can be made to any other phone, including landlines and the app can be used to make international calls for up to 98% less cost than with traditional carriers. Rebtel is becoming a big player in the market on the basis of its high quality and low cost of service. This is where other services like Rebtel are really useful. There is often a greater need to contact friends, relatives and business associates across multi platforms, connecting from the internet to mobile phones and land lines. Unfortunately the same applies across the market and there are no ubiquitous, far-reaching cross-app services. For example, a user of Skype has to pay to contact to someone who doesn’t have Skype. There are however certain limitations, with regards to contacting people outside of that particular service’s app. Many services exist to give users the option of making free calls via Wi-fi which is great for the market. It can also be such that each call requires a series of steps to connect, something that is far from convenient. Apps can be bought from the iPhone store that promise ‘free WiFi calls’, but many either have a catch that minutes are still deducted from the carrier’s phone plan or that they require lengthy and complicated configurations to work. The iStore isn’t without its critics and some cheap calling apps have been known to have been blocked on iPhones. Some mobile phone carriers have attempted to offer free calling over WiFi, but such plans rarely last long as they resort to their core products and services instead – which is the real cash cow for them. Often a ‘free WiFi calling solution” is offered, but the reality turns out to be either costly due to hidden charges or results in bad service with horrible connections, dropped calls and “out of service” areas. Making free WiFi calls on mobile phones or PCs has often involved having to engage in complicated workarounds with PBX systems, SIP accounts, hard to configure apps and forwarding setups. Free WiFi Calls Have Been Hard to Make for Years This can save people significant amounts of money every year, and is a huge advantage over a traditional phone service, expensive phone contracts (including 3G access) and even VoIP clients like Skype or Google Voice. Free Wi-Fi calling is a great way for those who need to make calls from their mobile phone or PC on a regular basis. However, tepache contains less sugar and is naturally flavored. It’s here that it gains the prebiotic and probiotic properties for which it’s so highly regarded.Įssentially, tepache and Kombucha have similarities in that they are both fermented and probiotic. Tepache is made up of pineapple pulp, spices, and brown sugar, which then ferments in barrels. In addition, the lack of caffeine avoids any adverse effects that a consumer may get from consuming caffeine from kombucha. Overall, De La Calle’s tepache has less sugar than kombucha. So Which Is Healthier? Synergy Kombucha or De La Calle’s Tepache?īoth drinks have great health benefits and suit different needs based on what you are looking to get out of your drink. De La Calle’s tepache is made from pineapple peel as a base, while Synergy Kombucha is added to tea.De La Calle’s tepache only requires fermentation for three to four days. When you add a SCOBY into sweetened tea and let it ferment for 1–4 weeks, you get kombucha.Tepache ferments without the aid of a SCOBY. SCOBY is a symbiotic culture of yeast and bacteria that aids in the fermentation process. De La Calle’s tepache does not require a SCOBY.Unlike kombucha, which is made from tea, tepache doesn’t contain caffeine.De La Calle’s tepache is naturally low in sugar.De La Calle’s tepache is naturally flavored.Synergy Kombucha is two servings per bottle. The serving size for De La Calle’s can is one serving per can.Tepache is less overbearing in taste than kombucha.De La Calle’s tepache comes in five flavors, while Synergy Kombucha has over fifty flavors.Synergy Kombucha is bottled, while De La Calle’s tepache is canned.Specifically, when comparing De La Calle’s tepache and Synergy Kombucha, they deviate in the following ways: While tepache and kombucha are both fermented bubbly beverages, there are many differences between them. How Is De La Calle’s Tepache Not Like Synergy Kombucha? There are health benefits to drinking kombucha, including those benefits associated with the consumption of probiotics which promote good gut health. The resulting liquid contains vinegar, B vitamins, and a number of other chemical compounds. Then, one allows the mix to ferment using the SCOBY. Kombucha tea is made by adding a colony of bacteria and yeast to sugar and tea. Tepache uses clean and simple ingredients. Depending on the flavor, some kombuchas can have up to 28 grams of sugar in them. Many attributes of tepache actually make it healthier than kombucha. These organic pineapples are the base of their tepache. De La Calle’s tepache only uses organic pineapples grown right in the heart of Mexico, where over 540,000 tons of fresh fruit is grown every year. De La Calle’s tepache is made from pineapple rinds as well as a blend of spices and aromatics. ![]() What Is in De La Calle’s Tepache?ĭe La Calle uses organic ingredients. De La Calle takes this iconic beverage and adds in unique regional flavors from around Mexico, creating combinations that are somehow nostalgic and modern at the same time. You can buy cold baggies of tepache on the streets of many Mexican cities for a cool, refreshing treat. This is because the ingredients change based on whether or not there are certain ingredients available to each locale. The recipes have been passed down for generations and vary depending on the region they originate from. There are countless variations to the drink. ![]() In fact, thousands of recipes for tepache exist. The Maya would often add different aromatics and herbs to its preparation. In Mayan culture, it was considered a sacred drink. ![]() In Central Mexico, locals have been fermenting pineapple into this refreshing concoction for centuries. Tepache is one of the most traditional and beloved drinks found in Mexico. ![]() Paul Leka, an East Coast record producer, brought the band to his recording studio in Bridgeport, Connecticut where it recorded original material for its first album. Louis, Missouri-based radio station KSHE, whose status as one of America's most influential rock stations boosted their platform beyond the Midwest. The Midwestern United States was the original REO Speedwagon fan stronghold and is pivotal in this period of the band's history. With Richrath on board, the regional popularity of the band grew tremendously. ![]() He is quoted as saying "I'm going to be a part of that band whether they like it or not", and then went about making it happen. Richrath had driven 100 miles (160 km) to see the band and become a part of it. Richrath was a Peoria, Illinois-based guitarist and prolific songwriter who brought fresh original material to the band. Steve Scorfina (who would go on to found progressive rock/ album-oriented rock band Pavlov's Dog) came aboard for over a year, composing with the band and performing live, before being replaced by Gary Richrath in late 1970. Fiorio then departed in late 1969, eventually assuming the name Duke Tumatoe, and went on to form the All Star Frogs. ![]() Crownover played guitar for the group until mid-1969 when Bill Fiorio replaced him. When Mike Blair left the band in mid-1968, Gregg Philbin replaced Blair, Marty Shepard played trumpet and Joe McCabe played sax until McCabe moved to Southern Illinois University. In early 1968, Terry Luttrell became lead singer, and Bob Crownover joined as the guitar player, replacing Matt. The first lineup consisted of Doughty on keyboards, Gratzer on drums and vocals, Joe Matt on guitar and vocals, Mike Blair on bass and vocals. They continued to perform cover songs in campus bars, fraternity parties, and university events. An advertisement in the school newspaper produced their first job, a fraternity party that turned into a food fight. Rather than pronouncing REO as a single word as the motor company did (" REE-oh"), they chose to spell the word out, pronouncing each letter individually ("R-E-O"). Doughty had seen the name written across the blackboard when he walked into his History of Transportation class on the first day they had decided to look for a name. They named the band REO Speedwagon, from the REO Speed Wagon, a 1915 truck that was designed by Ransom Eli Olds. The members returned to school in the fall of 1967 and had their first rehearsal before classes started. On his Farfisa organ, he learned " Light My Fire" by The Doors. They made a list of songs to learn over the summer break, and Doughty landed a summer job to buy his first keyboard. On the last day of the university's spring semester, guitarist Joe Matt called the band's leader and told him that he, drummer Gratzer, and bassist Mike Blair had decided to leave the band to start a new one with Doughty. ![]() The keyboard player was the leader, but several other band members were unhappy with the situation. Gratzer had been a drummer since high school, and was playing in a local group on the weekends, while Doughty had learned some Beatles songs on his parents' piano.ĭoughty began to follow Gratzer's band, eventually sitting in on a song or two. They held an impromptu jam session in the basement of their Illinois Street Residence Hall dormitory and soon started a rock band. On his first night, he met fellow student Alan Gratzer. In the autumn of 1966, Neal Doughty entered the electrical engineering program at the University of Illinois in Champaign, Illinois, as a junior. To get Wrapped Bitcoin, you need to deposit native Bitcoin (BTC) to a wallet controlled by one of several WBTC merchants. Wrapped Bitcoin (WBTC)Ĭreated by BitGo in 2018, Wrapped Bitcoin (WBTC) is a simple ERC20 token that represents Bitcoin on the Ethereum blockchain. To help make things clear, we take a look at five of the most popular DeFi assets today and examine what these tokens can do for you, and how they fit into the current DeFi landscape. In the last year, the number and variety of digital assets operating in the decentralized finance (DeFi) niche has grown considerably, as ever more creative uses for blockchain technology and DeFi are unraveled.Īs a result, there are now hundreds of digital assets with a primarily DeFi use case, which can cause a great deal of confusion for those looking to wrap their head around the space, since many of these tokens have overlapping functions, while some have close to no real utility at all. Taken together, these five tokens cover more than half of the DeFi landscape in terms of market value.Wrapped Bitcoin (WBTC), DAI, Uniswap (UNI), Aave (AAVE), and Chainlink (LINK) are currently the most successful DeFi tokens.The DeFi landscape is growing exponentially, but not all new DeFi tokens have true value or utility.“I can see a very strong community emerging around COMP now given the wide range of people earning it it’s the new lenders flowing in over the next weeks and months that will really make a difference,” he concluded as he predicted a potential rise to the top position for Compound COMP. Here’s a few things I got wrong.Īs you can see above, the founder of Synthetix (a platform creating synthetic assets for DeFi) shared his thoughts and offered praise to Compound regarding the successful launch of their token. So to that end, I definitely did not see this COMP launch playing out like this. One of the most critical things you can do as an investor imo is not succumb to hindsight bias. Pushing the combined market cap of DeFi tokens to over $3.2 billion one week after the total capitalization of the sector crossed the $2 billion mark, COMP has definitely done a good thing for DeFi tokens – which now represent more than 1% of the total crypto asset market cap for the first time ever. In other words, this is nearly 17% of the total funds currently allocated to DeFi. With the rise of the total value of USD locked in Compound COMP, we can now see that this is the second largest DeFi protocol by assets under management (AUM), increasing by around 48% in a day to reach $176.6 million in locked funds. Now, Compound comprises an algorithmic protocol for decentralized passive interest generation on Ethereum (ETH), and the project’s ERC-20 token affords voting rights to holders and allows them to propose alterations to the protocol’s code. The altcoin news then showed that it launched community governance for the protocol. The Compound COMP token started its distribution on Monday. We can also see that Compound COMP is also the 20th ranked crypto asset overall by its market cap, nudging the second largest stablecoin by capitalization – USD Coin (USDC) out of the top 20. Compound’s market cap of nearly $740 million is now 35% greater than Maker and its $547 million market cap for MKR, according to the market data source DeFiMarketCap.io. The token has since pulled back around 20% from the local highs over $100. This cryptocurrency is now viral in the world of decentralized finance and as updates from the cryptonews show, it is rising in terms of popularity, too.ĬOMP overtook MakerDAO and its MKR token by market cap as it rallied by more than 60% in just a few hours. The brand new token called Compound COMP has emerged as the largest DeFi token by market capitalization and topped the rankings on its first day of trading. |
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